Jadavji Laboratory



Deparment Biomedical Sciences, Division of Molecular and Integrative Physiology

Southern Illinois University



Publications


Preprints too!


An updated and expanded characterization of the biological sciences academic job market


Brooklynn Flynn, A. Kozik, You Cheng, Ada Hagan, Jennifer Ng, Christopher T. Smith, Amanda Haage, N. Jadavji

bioRxiv, 2024


Maternal dietary deficiencies in folic acid and choline change metabolites levels in offspring after ischemic stroke


Fazian Anwar, Mary-Tyler Mosley, Paniz Jasbi, Jinhua Chi, Haiwei Gu, N. Jadavji

bioRxiv, 2024


Apoptosis is increased in cortical neurons of female Marfan Syndrome mice


M. Esfandiarei, Faizan Anwar, Manogna Nuthi, Alisha Harrison, M. Barrameda, T. Curry, Kasey Pull, T. Currier Thomas, N. Jadavji

bioRxiv, 2024


Maternal Dietary Deficiency in Choline Reduced Levels of MMP-2 Levels in Blood and Brain Tissue of Male Offspring Mice


M. Esfandiarei, Shawn G. U. Strash, Amanda Covaleski, Sharadyn Ille, Wei-dang Li, N. Jadavji

Cells, 2024


Maternal dietary deficiency in choline reduced levels of MMP-2 levels in blood and brain tissue of male offspring mice


Mitra Esfandiarei, Shawn G. U. Strash, Amanda Covaleski, Sharadyn Ille, Wei-dang Li, N. Jadavji

bioRxiv, 2024


Over supplementation of folic acid reduces survival 24 hours after hypoxia in male and female Drosophila melanogaster


Siddarth Gunnala, Alisha Harrison, Amber Juba, Paula Ashcraft, Teodoro Bottiglieri, Lori M Buhlman, N. Jadavji

bioRxiv, 2024


The U.S. faculty job market survives the SARS-CoV-2 global pandemic


A. Kozik, Ada Hagan, N. Jadavji, Christopher T. Smith, Amanda Haage

bioRxiv, 2023


Editorial: Women in nutrition and brain health


E. Hogervorst, C. Haskell-Ramsay, N. Jadavji

Frontiers in Nutrition, 2023


Impact of maternal dietary folic acid or choline dietary deficiencies on vascular function in young and middle-aged female mouse offspring after ischemic stroke.


Kasey Pull, Robert Folk, Jeemin Kang, Shaley Jackson, Brikena Gusek, Mitra Esfandiarei, N. Jadavji

American Journal of Physiology. Heart and Circulatory Physiology, 2023


Maternal dietary deficiencies in folic acid or choline worsen stroke outcomes in adult male and female mouse offspring


McCoy Clementson, L. Hurley, Sarah Coonrod, Calli Bennett, Purvaja Marella, Agnes S. Pascual, Kasey Pull, Brandi L. Wasek, T. Bottiglieri, O. Malysheva, M. Caudill, N. Jadavji

Neural Regeneration Research, 2023


Editorial: Reproducibility in neuroscience


N. Jadavji, Nele A. Haelterman, R. Sud, A. Antonietti

Frontiers in Integrative Neuroscience, 2023


Impact of increasing one-carbon metabolites on traumatic brain injury outcome using pre-clinical models


Sanika M. Joshi, Theresa Currier Thomas, N. Jadavji

Neural Regeneration Research, 2023


The Role of One-Carbon Metabolism in Healthy Brain Aging


Sapna Virdi, Abbey M. McKee, Manogna Nuthi, N. Jadavji

Nutrients, 2023


Ischemic Stroke and Dietary Vitamin B12 Deficiency in Old-Aged Females: Impaired Motor Function, Increased Ischemic Damage Size, and Changed Metabolite Profiles in Brain and Cecum Tissue


Joshua Poole, Paniz Jasbi, Agnes S. Pascual, Sean North, Neha Kwatra, V. Weissig, Haiwei Gu, T. Bottiglieri, N. Jadavji

bioRxiv, 2022


Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring


McCoy Clementson, L. Hurley, Sarah Coonrod, Calli Bennett, Purvaja Marella, Agnes S. Pascual, Kasey Pull, Brandi L. Wasek, T. Bottiglieri, O. Malysheva, Marie A. Ca udill, N. Jadavji

bioRxiv, 2022


Editorial: The role of epigenetics in neuropsychiatric disorders


M. Shirinian, Chong Chen, S. Uchida, N. Jadavji

Frontiers in Molecular Neuroscience, 2022


The role of dietary supplements that modulate one-carbon metabolism on stroke outcome


G. Yahn, J. Leoncio, N. Jadavji

Current opinion in clinical nutrition and metabolic care, 2021


Identification and Development of Therapeutics for COVID-19


H. Rando, Nils Wellhausen, Soumita Ghosh, Alexandra J. Lee, A. A. Dattoli, Fenglin Hu, J. B. Byrd, Diane N. Rafizadeh, Yanjun Qi, Yuchen Sun, J. Field, Marouen Ben Guebila, N. Jadavji, R. Lordan, Ashwin N. Skelly, Bharath Ramsundar, C. Brueffer, Jinhui Wang, R. Goel, YoSon Park, COVID-19 Review Consortium, S. Boca, A. Gitter, C. Greene

arXiv.org, 2021


Writing an effective and supportive recommendation letter


S. Sarabipour, Sarah J. Hainer, Emily Furlong, N. Jadavji, Charlotte M. de Winde, Natalia Z. Bielczyk, Aparna P Shah

The FEBS Journal, 2021


Building and sustaining mentor interactions as a mentee


S. Sarabipour, Sarah J. Hainer, Feyza Nur Arslan, Charlotte M. de Winde, Emily Furlong, Natalia Z. Bielczyk, N. Jadavji, Aparna P Shah, Sejal Davla

The FEBS Journal, 2021


A community-led initiative for training in reproducible research


Susann Auer, Nele A. Haelterman, T. Weissgerber, Jeffrey C. Erlich, Damar Susilaradeya, M. Julkowska, M. A. Gazda, B. Schwessinger, N. Jadavji

eLife, 2021


Dietary folic acid deficiency impacts hippocampal morphology and cortical acetylcholine metabolism in adult male and female mice


Calli Bennett, Jacalyn M. Green, M. Ciancio, J. Góral, L. Pitstick, M. Pytynia, Alice Meyer, Neha Kwatra, N. Jadavji

bioRxiv, 2020


Towards inclusive funding practices for early career researchers


Charlotte M. de Winde, S. Sarabipour, H. Carignano, Sejal Davla, D. Eccles, Sarah J. Hainer, Mansour Haidar, V. Ilangovan, N. Jadavji, Paraskevi Kritsiligkou, Tai-Ying Lee, Freyja Ólafsdóttir

Journal of Science Policy & Governance, 2020


Role of vitamin B12 deficiency in ischemic stroke risk and outcome


G. Yahn, J. Abato, N. Jadavji

Neural Regeneration Research, 2020


The Role of One-Carbon Metabolism After Ischemic Stroke in an Aged Mouse Model


Hannah Mosnier, E. Kelly, K. Lawrence, S. Cruickshank, S. Stacey, Adelina McCall, Sunny Dhatt, E. Arning, T. Bottiglieri, N. Jadavji

Current Developments in Nutrition, 2020


The role of maternal diet on offspring gut microbiota development: A review


Hiba Al Rubaye, Chelsea C. Adamson, N. Jadavji

Journal of Neuroscience Research, 2020


SARS-CoV-2 and COVID-19: An Evolving Review of Diagnostics and Therapeutics


H. Rando, C. Greene, Michael P. Robson, S. Boca, Nils Wellhausen, R. Lordan, C. Brueffer, S. Ray, L. D. McGowan, A. Gitter, Ronnie M. Russell, A. A. Dattoli, Ryan Velazquez, J. Barton, J. Field, Bharath Ramsundar, Adam L. Maclean, Alexandra J. Lee, Fenglin Hu, N. Jadavji, Elizabeth A Sell, Jinhui Wang, Diane N. Rafizadeh, Ashwin N. Skelly, Marouen Ben Guebila, Likhitha Kolla, D. Manheim, Soumita Ghosh, Matthias Fax, J. B. Byrd, YoSon Park, Yael Evelyn Marshall, V. Bansal, Stephen Capone, John J. Dziak

2020


The Antioxidant Role of One-Carbon Metabolism on Stroke


Kassidy Burgess, Calli Bennett, Hannah Mosnier, Neha Kwatra, Forrest Bethel, N. Jadavji

Antioxidants, 2020


The changing postdoc and key predictors of satisfaction with professional training


Kathleen Van Benthem, M. N. Adi, Christopher T. Corkery, Jiro Inoue, N. Jadavji

Studies in Graduate and Postdoctoral Education, 2020


Linking homocysteine, B vitamins, and choline to ischemic stroke risk


Mahira Moftah, Joshua T. Emmerson, N. Jadavji

2020


Reproducibility for everyone: a community-led initiative with global reach in reproducible research training


Susann Auer, Nele A. Haelterman, T. Weissgerber, Jeffrey C. Erlich, Damar Susilaradeya, M. Julkowska, M. A. Gazda, Angela Abitua, Anzela Niraulu, Aparna P Shah, April Clyburne-Sherin, Benoit Guiquel, Bradly Alicea, Caroline M Lamanna, D. Ganguly, Eric J Perkins, H. Jambor, Ian Man Ho Li, J. Tsang, J. Kamens, L. Teytelman, Mariella Paul, Santosh Phuyal, Nicolas M. Schmelling, P. Crisp, S. Sarabipour, Sonali Roy, Susanna M. Bachle, Tuan Khoi Tran, T. Ford, V. Steeves, V. Ilangovan, B. Schwessinger, N. Jadavji

2020


Reduced Hippocampal Neurogenesis in Mice Deficient in Apoptosis Repressor with Caspase Recruitment Domain (ARC)


G. Kronenberg, K. Gertz, R. Uhlemann, M. T. Kuffner, Imke Kirste, Junfeng An, N. Jadavji, B. Schott, T. Scheffel, M. Endres, R. Hellweg, C. Harms

Neuroscience, 2019


Methylenetetrahydrofolate reductase deficiency alters cellular response after ischemic stroke in male mice


J. Abato, Mahira Moftah, G. Cron, Patrice D. Smith, N. Jadavji

bioRxiv, 2019


A survey-based analysis of the academic job market


Jason D. Fernandes, S. Sarabipour, Christopher T Smith, Natalie M. Niemi, N. Jadavji, A. Kozik, A. Holehouse, V. Pejaver, Orsolya Symmons, Alexandre W. Bisson Filho, Amanda Haage

bioRxiv, 2019


Postnatal gestational age estimation via newborn screening analysis: application and potential


Lindsay A Wilson, Malia S Q Murphy, R. Ducharme, K. Denize, N. Jadavji, B. Potter, J. Little, P. Chakraborty, S. Hawken, K. Wilson

Espert Review of Proteomics, 2019


MTHFR-deficiency Increases Ischemic Damage Through Reduced Neuronal and Astrocytes Viability and Changes in the Cellular Response (P01-020-19).


Mahira Moftah, G. Cron, Joshua T. Emmerson, Bill Willmore, Patrice D. Smith, N. Jadavji

Current Developments in Nutrition, 2019


Role of behavioral training in reducing functional impairments after stroke


Mahira Moftah, N. Jadavji

Neural Regeneration Research, 2019


One-carbon metabolism supplementation improves outcome after stroke in aged male MTHFR-deficient mice


N. Jadavji, Hannah Mosnier, E. Kelly, K. Lawrence, S. Cruickshank, S. Stacey, Adelina McCall, Sandeep Dhatt, E. Arning, T. Bottiglieri, Patrice D. Smith

Neurobiology of Disease, 2019


Paraquat Exposure Increases Oxidative Stress Within the Dorsal Striatum of Male Mice With a Genetic Deficiency in One-carbon Metabolism.


N. Jadavji, Lauren K. Murray, Joshua T. Emmerson, Chris Rudyk, S. Hayley, Patrice D. Smith

Toxicological Sciences, 2019


Maternal oversupplementation with folic acid and its impact on neurodevelopment of offspring


Lauren K. Murray, Mark J Smith, N. Jadavji

Nutrition reviews, 2018


Recombinant growth differentiation factor 11 influences short-term memory and enhances Sox2 expression in middle-aged mice


Min Zhang, N. Jadavji, Hyung-Suk Yoo, Patrice D. Smith

Behavioural Brain Research, 2018


A genetic deficiency in folic acid metabolism impairs recovery after ischemic stroke


N. Jadavji, Joshua T. Emmerson, Ushananthini Shanmugalingam, A. MacFarlane, W. Willmore, Patrice D. Smith

Experimental Neurology, 2018


Reduced brain volume and impaired memory in betaine homocysteine S-methyltransferase knockout mice.


E. A. Prieur, E. Pjetri, S. Zeisel, N. Jadavji

Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2017


Impact of dietary supplementation of one-carbon metabolism on neural recovery


Joshua T. Emmerson, Lauren K. Murray, N. Jadavji

Neural Regeneration Research, 2017


Increased homocysteine levels impair reference memory and reduce cortical levels of acetylcholine in a mouse model of vascular cognitive impairment


K. Dam, Martina Füchtemeier, T. Farr, Philipp Boehm-Sturm, Marco Foddis, U. Dirnagl, O. Malysheva, M. Caudill, N. Jadavji

Behavioural Brain Research, 2017


B-vitamin and choline supplementation increases neuroplasticity and recovery after stroke


N. Jadavji, Joshua T. Emmerson, A. MacFarlane, W. Willmore, Patrice D. Smith

Neurobiology of Disease, 2017


High dietary folate in pregnant mice leads to pseudo-MTHFR deficiency and altered methyl metabolism, with embryonic growth delay and short-term memory impairment in offspring


Renata H. Bahous, N. Jadavji, L. Deng, M. Cosín-Tomás, Jessica Lu, O. Malysheva, K. Leung, Ming-kai Ho, M. Pallàs, P. Kaliman, N. Greene, B. Bedell, M. Caudill, R. Rozen

Human Molecular Genetics, 2017


Neurogenesis Unchanged by MTHRF Deficiency in Three-Week-Old Mice


G. Owens, Patrice D. Smith, N. Jadavji

2016


Fractionated low-dose exposure to ionizing radiation leads to DNA damage, epigenetic dysregulation, and behavioral impairment


Igor Koturbash, N. Jadavji, Kristy R. Kutanzi, Rocio Rodriguez-Juarez, Dmitry Kogosov, G. Metz, O. Kovalchuk

Environmental epigenetics, 2016


Granulocyte macrophage colony‐stimulating factor treatment results in recovery of motor function after white matter damage in mice


Jennifer K Theoret, N. Jadavji, Min Zhang, Patrice D. Smith

European Journal of Neuroscience, 2016


The pleiotropic effects of tissue plasminogen activator in the brain: implications for stroke recovery


Julia A. Grummisch, N. Jadavji, Patrice D. Smith

Neural Regeneration Research, 2016


tPA promotes cortical neuron survival via mTOR-dependent mechanisms


Julia A. Grummisch, N. Jadavji, Patrice D. Smith

Molecular and Cellular Neuroscience, 2016


Role of granulocyte macrophage colony stimulating factor in regeneration of the central nervous system


Ushananthini Shanmugalingam, N. Jadavji, Patrice D. Smith

Neural Regeneration Research, 2016


Methylenetetrahydrofolate reductase deficiency alters levels of glutamate and γ-aminobutyric acid in brain tissue


N. Jadavji, F. Wieske, U. Dirnagl, C. Winter

Molecular Genetics and Metabolism Reports, 2015


Elevated levels of plasma homocysteine, deficiencies in dietary folic acid and uracil–DNA glycosylase impair learning in a mouse model of vascular cognitive impairment


N. Jadavji, T. Farr, Janet Lips, A. Khalil, Philipp Boehm-Sturm, Marco Foddis, C. Harms, Martina Füchtemeier, U. Dirnagl

Behavioural Brain Research, 2015


Mouse model for deficiency of methionine synthase reductase exhibits short-term memory impairment and disturbances in brain choline metabolism.


N. Jadavji, Renata H. Bahous, L. Deng, O. Malysheva, Marilyn Grand'maison, B. Bedell, M. Caudill, R. Rozen

Biochemical Journal, 2014


Severe methylenetetrahydrofolate reductase deficiency in mice results in behavioral anomalies with morphological and biochemical changes in hippocampus.


N. Jadavji, L. Deng, D. Leclerc, O. Malysheva, B. Bedell, M. Caudill, R. Rozen

Molecular Genetics and Metabolism, 2012


Predictable stress versus unpredictable stress: A comparison in a rodent model of stroke


Fabíola C. R. Zucchi, S. Kirkland, N. Jadavji, L. V. Waes, A. Klein, Rebecca D. Supina, G. Metz

Behavioural Brain Research, 2009


Stress accelerates neural degeneration and exaggerates motor symptoms in a rat model of Parkinson's disease


L. K. Smith, N. Jadavji, Keri L. Colwell, S. Katrina Perehudoff, G. Metz

European Journal of Neuroscience, 2008


Supporting Undergraduate Research


Farhan Ali, N. Jadavji, Willie Ong, K. Pandey, A. Patananan, Harsha K. Prabhala, Christine Hong-Ting Yang

Science, 2007


Silencing Huntington ’ s chorea : Is RNA Interference a Potential Cure ?


N. Jadavji, Afra Foroud, I. Whishaw, G. Metz

2007


Modulation of motor function by stress: a novel concept of the effects of stress and corticosterone on behavior


G. Metz, N. Jadavji, L. K. Smith

European Journal of Neuroscience, 2005