Jadavji Laboratory



Biomedical Sciences

Southern Illinois University



Assessing Spatial Working Memory Using the Spontaneous Alternation Y-maze Test in Aged Male Mice.


Journal article


E. A. Prieur, N. Jadavji
Bio-protocol, 2019

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APA   Click to copy
Prieur, E. A., & Jadavji, N. (2019). Assessing Spatial Working Memory Using the Spontaneous Alternation Y-maze Test in Aged Male Mice. Bio-Protocol.


Chicago/Turabian   Click to copy
Prieur, E. A., and N. Jadavji. “Assessing Spatial Working Memory Using the Spontaneous Alternation Y-Maze Test in Aged Male Mice.” Bio-protocol (2019).


MLA   Click to copy
Prieur, E. A., and N. Jadavji. “Assessing Spatial Working Memory Using the Spontaneous Alternation Y-Maze Test in Aged Male Mice.” Bio-Protocol, 2019.


BibTeX   Click to copy

@article{e2019a,
  title = {Assessing Spatial Working Memory Using the Spontaneous Alternation Y-maze Test in Aged Male Mice.},
  year = {2019},
  journal = {Bio-protocol},
  author = {Prieur, E. A. and Jadavji, N.}
}

Abstract

The global population is aging and the prevalence of age-related diseases, such as Alzheimer's disease and vascular dementia is increasing. Understanding functional impairments and disease processes is of vital importance in order to develop effective therapeutics. Using the natural exploratory behavior of mice, the spontaneous alternation y-maze can assess short-term spatial working memory. The protocol for y-maze testing is straightforward and requires minimal resources, as well as animal training and output. Therefore, it can be broadly applied to study short-term memory in aged rodent models.