Journal article
Bio-protocol, 2019
APA
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Prieur, E. A., & Jadavji, N. (2019). Assessing Spatial Working Memory Using the Spontaneous Alternation Y-maze Test in Aged Male Mice. Bio-Protocol.
Chicago/Turabian
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Prieur, E. A., and N. Jadavji. “Assessing Spatial Working Memory Using the Spontaneous Alternation Y-Maze Test in Aged Male Mice.” Bio-protocol (2019).
MLA
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Prieur, E. A., and N. Jadavji. “Assessing Spatial Working Memory Using the Spontaneous Alternation Y-Maze Test in Aged Male Mice.” Bio-Protocol, 2019.
BibTeX Click to copy
@article{e2019a,
title = {Assessing Spatial Working Memory Using the Spontaneous Alternation Y-maze Test in Aged Male Mice.},
year = {2019},
journal = {Bio-protocol},
author = {Prieur, E. A. and Jadavji, N.}
}
The global population is aging and the prevalence of age-related diseases, such as Alzheimer's disease and vascular dementia is increasing. Understanding functional impairments and disease processes is of vital importance in order to develop effective therapeutics. Using the natural exploratory behavior of mice, the spontaneous alternation y-maze can assess short-term spatial working memory. The protocol for y-maze testing is straightforward and requires minimal resources, as well as animal training and output. Therefore, it can be broadly applied to study short-term memory in aged rodent models.