Jadavji Laboratory


Deparment Biomedical Sciences, Division of Molecular and Integrative Physiology

Southern Illinois University



People


Link to Dr. Jadavji's CV

Dr. Nafisa (n uh - f ee - s ah) M. Jadavji (j aa - d uh v - j ee) is a Neuroscientist and mother. She is an Assistant Professor at Southern Illinois University Carbondale. She completed her doctoral training at McGill University in Montréal, Canada.  

The Jadavji laboratory investigates how the brain responds to different biological processes throughout the lifespan. More specifically, her laboratory studies how the brain responds to changes in one-carbon metabolism, with a specific focus on maternal nutrition contributions to offspring neurodevelopment, neurological diseases (e.g. ischemic stroke and vascular dementia), and aging.  

Her lab has contributed to the neuroscience aging research including providing an understanding on how dietary deficiencies in vitamin B12 increase apoptosis in brain tissue and change mitochondria metabolites within the gut after an ischemic stroke. They have also shown that a maternal diet deficient in either choline or folic acid during pregnancy negatively impacts ischemic stroke outcome in male and female offspring. This work has focused on behavioral outcomes, brain tissue analysis, stool metabolites, and blood flow within the brain. 

Dr. Jadavji has received funding from the US Department of Agriculture (USDA), National Institutes of Health – NINDS (US), Arizona Department of Health, American Heart Association (US), Federation of European Neuroscience Society (Europe), NeuroWIND (Germany), Canadian Association for Neuroscience, Canadian Institutes of Health Research, National Science & Engineering Research Council (Canada), International Brain Research Organization, Parkinson's disease Foundation (US), Burroughs Wellcome Fund (US) and Fonds de la recherché en santé Québec (Canada). 

Dr. Jadavji’s research has been published in Biochemical Journal, Neuroendocrinology, Experimental Neurology, Journal of Neuroscience, Human Molecular Genetics, Nutrition Reviews, Toxicological Science, European Journal of Neuroscience, Neural Regeneration Research, Nutritional Neuroscience, Nutrients, and Neurobiology of Disease.  Dr. Jadavji has published 75 peer reviewed papers, over 150 abstracts, and given 60 invited talks about the research conducted in her laboratory.  She has also posted several preprints.  

Dr. Jadavji is an Editorial member at Scientific Reports, Bioprotocols, Metabolites, Nutrients, and Journal of Stroke and Cerebrovascular Diseases journals. She is the Chair of the Board of Directors for the Journal of Young Investigators (JYI) and Chair of the Advisory Board for Reproducibility for Everyone (R4E). 

Dr. Jadavji has supervised and mentored over 80 undergraduate, graduate, and postdocs so far during her scientific career.  

When she is not in the laboratory, teaching, or writing, Dr. Jadavji enjoys exercising, cooking, and baking gluten free treats. She is also an avid traveler and knitter. 

Elijah Neitzel

My name is Elijah Neitzel, and I am currently a sophomore at Southern Illinois University Carbondale. I am majoring in Biology and minoring in Chemistry. In the future, I hope to attend medical school and wish to become an emergency physician. I am very excited, and interested in working for the Jadavji Laboratory! Learning more about neuroscience and the brain is one of my favorite things to do. In my free time, I like to lift weights, play music, hang out with friends, and read

Lillian Schuler
My name is Lillian Schuler, and I am currently a freshman at Southern Illinois University. I am majoring in Physiology with a minor in chemistry. In the future, I hope to attend medical school and become a specialized physician. I am so excited to be a part of the Jadavji lab and learn more about the field of neurology and research techniques. In my free time, I enjoy reading fantasy and science fiction books, learning languages, and cooking.

Awards:
  • 2026-27 Susan C. Thrasher Undergraduate Research Fund
  • 2026 Journal of Young Investigator Grant
Publications:
Abell AJ, Schuler LK, Jadavji NM* (2026). Maternal dietary intake of folic acid, vitamin B12, and choline impacts offspring DNA methylation after birth. Nutrients, 18: 3306. *Featured on cover of Nutrients October 2026
Quentin Pedtke
I currently am attending Southern Illinois University Carbondale where I am majoring in Physiology with a double minor in Chemistry and Spanish. I plan to pursue a career in the medical field after, where I am eager to becoming a trauma surgeon. I am thrilled to be part of the Jadavji Laboratory, and I am excited to gain more knowledge about the field of neurology. During my free time, I enjoy hanging out with friends and family where I like to run, workout, travel to tropical destinations, and relax. 

Awards:
2026-27 Research-Enriched Academic Challenge Award
 
Tia Jankovics
My name is Tia Jankovics, and I am in my sophomore year at Southern Illinois University majoring in Biomedical Science. In the future, I would like to continue my education in medical school to work towards becoming a family physician. I am also on the SIU swim team and love to spend time with my teammates outside of school and the pool 
The Unsung Heroes of Research. We strive to treat our animal subjects humanely and to follow the 3Rs of animal research.

Jadavji Laboratory Alumni

41. Alek Abell, BS - Biomedical Sciences Undergraduate Student

Publication:

Abell AJ, Schuler LK, Jadavji NM* (2026). Maternal dietary intake of folic acid, vitamin B12, and choline impacts offspring DNA methylation after birth. Nutrients, 18: 3306. *Featured on cover of Nutrients October 2026

Award:

2025 Journal of Young Investigator Grant

40. Farwah Wasiq, BS - SIU SOM MPEE Student

Current Position: SOM Medical Student

39. Nora Jones - Biomedical Sciences Undergraduate Student

Publications:

Jones N, Binte S, Jadavji NM* (2026) Highlighting the mechanisms through which increased dietary folic acid and choline impact regeneration in the brain after damage. Neural Regeneration:21. doi: 10.4103/NRR.NRR-D-25-01911 

Award:

2025 Journal of Young Investigator Grant

38. Elizabeth Pineda

Award

2026 Journal of Young Investigator Grant

37. Riley McCabe - Physiology Undergraduate Student

Current Position: Physiology Undergraduate Student

Publication:

Joshi SM, McCabe R, Jadavji NM * (2024) Dietary interventions and neurobehavior in society. Nutritional Neuroscience: from bench to bed side. Editor: Reinaldo Oria, Joano Malva, Carlos Alexander Netto. Elsevier. (invited)

McCabe RM, Hurley L, Pull K, Jadavji NM* (2026) Immunotherapies for Ischemic Stroke Patients: Current Status and Future Directions. Medical Sciences: 14:111 

36. Gillian McDermott - SIU SOM MPEE Student

Current Position: SOM Medical Student

Publications:

Burrows P, Dhillon H, McDermott GE, Covaleski A, Manfredi L, Beach TG, Serrano GE, Jadavji NM* (2026). Ischemic stroke increases levels of the folate receptor and one-carbon enzymes in male and female brain tissue.Translational Stroke Research, 17:87 

35. Meher Garg - High school SIU STEM Program Student, 2025 and 2026

Current position: High School Student


34. Hassanat Etti-Balogun - Graduate Student SIUC

Award: Florence M. Foote Scholarship

33. Kalysta Conley - Physiology Undergraduate student 

Current position: Physican Assistant Student

Gunther Strash, M.B.S, – College of Osteopathic Medicine

Current position: Doctor of Osteopathic Medicine student, Midwestern University

Publications: 

Esfandiarei M, Strash SGU, Covaleski A, Ille S, Li W, Jadavji NM* (2024) Maternal dietary deficiency in choline reduced levels of MMP-2 levels in blood and brain tissue of male offspring mice. Cells: 13.1472 

PREPRINT: Esfandiarei M, Strash SGU, Covaleski A, Ille S, Li W, Jadavji NM* (2024) Maternal dietary deficiency in choline reduced levels of MMP-2 levels in blood and brain tissue of male offspring mice. https://www.biorxiv.org/content/10.1101/2024.07.15.603575v1

32. Alisha Harrison, BA – Sr. Research Specialist, Midwestern University

Current position: Senior Research Specialist

Publications:

 Esfandiarei M, Anwar F, Nuthi M, Harrison A, Barrameda ME, Curry T, Pull K, Currier Thomas T, Jadavji NM (2025) Apoptosis is increased in cortical neurons of female Marfan Syndrome mice. microPublication Biology. 10.17912/micropub.biology.001651. PMID: 40896254. 

Gunnala S, Harrison A, Juba A, Ashcraft P, Garg M, Bottiglieri T, Buhlman LM, Jadavji NM* (2026) Increased dietary levels of folic acid reduce survival and alters climbing behaviors 24 hours after hypoxia in male and female Drosophila melanogaster. Behavioral Brain Research: 499: 115941

PREPRINT: Gunnala S, Harrison A, Juba A, Ashcraft P, Bottiglieri T, Buhlman LM, Jadavji NM (2024) Over supplementation of folic acid reduces survival 24 hours after hypoxia in male and female Drosophila melanogaster. https://www.biorxiv.org/content/10.1101/2024.10.23.619884v1 

PREPRINT: Esfandiarei M, Anwar F, Nuthi M, Harrison A, Barrameda ME, Curry T, Pull K, Currier Thomas T, Jadavji NM (2024) Apoptosis is increased in cortical neurons of female Marfan Syndrome mice. https://www.biorxiv.org/content/10.1101/2024.10.14.618278v1 

31. Mary-Tyler Mosley - Undergraduate Student

Current position: Undergraduate Student, Stanford University

Publications 

 Anwar F, Mosely MT, Jasbi P, Chi J, Gu H, Jadavji NM* (2024) Maternal dietary deficiencies in folic acid and choline change metabolites levels in offspring after ischemic stroke. Metabolites: 14.552. 

PREPRINT: Anwar F, Mosely MT, Jasbi P, Chi J, Gu H, Jadavji NM (2024) Maternal dietary deficiencies in folic acid and choline change metabolites levels in offspring after ischemic stroke. https://www.biorxiv.org/content/10.1101/2024.06.29.601358v2.full.pdf+html

30. Sharadyn Ille, B.S. – Doctor of Dental Medicine Student

Current position:  Resident, Periodontics, Western Virginia University 

 Publications: 

Esfandiarei M, Strash SGU, Covaleski A, Ille S, Li W, Jadavji NM* (2024) Maternal dietary deficiency in choline reduced levels of MMP-2 levels in blood and brain tissue of male offspring mice. Cells: 13.1472 

PREPRINT: Esfandiarei M, Strash SGU, Covaleski A, Ille S, Li W, Jadavji NM* (2024) Maternal dietary deficiency in choline reduced levels of MMP-2 levels in blood and brain tissue of male offspring mice. https://www.biorxiv.org/content/10.1101/2024.07.15.603575v1

Hurley L, Jauhal J, Ille S, Pull K, Malysheva OV, Jadavji NM. (2023). Maternal dietary deficiencies in one-carbon metabolism during early neurodevelopment result in larger damage volume, reduced neurodegeneration and neuroinflammation and changes in choline metabolites after ischemic stroke in middle-aged offspring. Nutrients. 15:1556  (Invited)

PREPRINT Hurley L, Jauhal J, Ille S, Pull K, Malysheva OV, Jadavji NM. (2023) Maternal dietary deficiencies in one-carbon metabolism during early neurodevelopment result in larger damage volume, reduced neurodegeneration and neuroinflammation and changes in choline metabolites after ischemic stroke in middle-aged offspring. https://www.biorxiv.org/content/10.1101/2023.02.15.528759v1

29. Faizan Anwar, BS  – College of Osteopathic Medicine 

Current position: Doctor of Osteopathic Medicine student, Midwestern University

Publications 

 Esfandiarei M, Anwar F, Nuthi M, Harrison, Barrameda ME, Curry T, Pull K, Currier Thomas T, Jadavji NM (2025) Apoptosis is increased in cortical neurons of female Marfan Syndrome mice. microPublication Biology. 10.17912/micropub.biology.001651. PMID: 40896254. 

PREPRINT: Esfandiarei M, Anwar F, Nuthi M, Harrison A, Barrameda ME, Curry T, Pull K, Currier Thomas T, Jadavji NM (2024) Apoptosis is increased in cortical neurons of female Marfan Syndrome mice. https://www.biorxiv.org/content/10.1101/2024.10.14.618278v1 

Anwar F, Mosely MT, Jasbi P, Chi J, Gu H, Jadavji NM* (2024) Maternal dietary deficiencies in folic acid and choline change metabolites levels in offspring after ischemic stroke. Metabolites: 14.552.

PREPRINT: Anwar F, Mosely MT, Jasbi P, Chi J, Gu H, Jadavji NM (2024) Maternal dietary deficiencies in folic acid and choline change metabolites levels in offspring after ischemic stroke. https://www.biorxiv.org/content/10.1101/2024.06.29.601358v2.full.pdf+html

28. Manogna Nuthi, BS - College of Osteopathic Medicine 

Current position: Doctor of Osteopathic Medicine student, Midwestern University

Publications 

 Esfandiarei M, Anwar F, Nuthi M, Harrison, Barrameda ME, Curry T, Pull K, Currier Thomas T, Jadavji NM (2025) Apoptosis is increased in cortical neurons of female Marfan Syndrome mice. microPublication Biology. 10.17912/micropub.biology.001651. PMID: 40896254. 

PREPRINT: Esfandiarei M, Anwar F, Nuthi M, Harrison A, Barrameda ME, Curry T, Pull K, Currier Thomas T, Jadavji NM (2024) Apoptosis is increased in cortical neurons of female Marfan Syndrome mice. https://www.biorxiv.org/content/10.1101/2024.10.14.618278v1 

Virdi S, McKee AM, Nuthi M, Jadavji NM* (2023). The role of one-carbon metabolism on healthy brain aging. Nutrients. 15: 3891. (IF =5.9) (invited)

27. Amanda Covaleski, B.S.  –  College of Pharmacy 

Current position:  Resident at VA Tennessee Valley 

Publications: 

Esfandiarei M, Strash SGU, Covaleski A, Ille S, Li W, Jadavji NM* (2024) Maternal dietary deficiency in choline reduced levels of MMP-2 levels in blood and brain tissue of male offspring mice. Cells: 13.1472 

PREPRINT: Esfandiarei M, Strash SGU, Covaleski A, Ille S, Li W, Jadavji NM* (2024) Maternal dietary deficiency in choline reduced levels of MMP-2 levels in blood and brain tissue of male offspring mice. https://www.biorxiv.org/content/10.1101/2024.07.15.603575v1

Burrows P, Dhillon H, McDermott GE, Covaleski A, Manfredi L, Beach TG, Serrano GE, Jadavji NM* (2026). Ischemic stroke increases levels of the folate receptor and one-carbon enzymes in male and female brain tissue.Translational Stroke Research, 17:87 

26. Brooklynn Flynn, BSc - College of Osteopathic Medicine 

Current position: Doctor of Osteopathic Medicine student, Midwestern University

Publications: 

Flynn B, Cheng L, Hagan A, Kozik AJ, Ng J, Smith CT, Haage A, Jadavji NM* (2024). An updated and expanded characterization of the biological sciences academic job market.  Frontiers in Research Metrics and Analytics: In press 

Petter Burrows, B.S. - College of Veterinary Medicine Fellow 2023

Current position: Small Animal Rotating Intern Department of Clinical Sciences Tufts University 

Publications: 

Burrows P, Dhillon H, McDermott GE, Covaleski A, Manfredi L, Beach TG, Serrano GE, Jadavji NM* (2026). Ischemic stroke increases levels of the folate receptor and one-carbon enzymes in male and female brain tissue.Translational Stroke Research, 17:87 

​​25. Siddarth Gunnala, MBS - Master of Biomedical Science and Doctor of Osteopathic Medicine Student

Current position: Doctor of Osteopathic Medicine student, Midwestern University

Publications: 

Gunnala S, Jadavji NM* (2026) Climbing Behavior of Drosophila melanogaster Larvae in Response to Hypoxia.Journal of Visualized Experiments: Encyclopedia of Experiments: 208. 

Gunnala S, Harrison A, Juba A, Ashcraft P, Garg M, Bottiglieri T, Buhlman LM, Jadavji NM* (2026) Increased dietary levels of folic acid reduce survival and alters climbing behaviors 24 hours after hypoxia in male and female Drosophila melanogaster. Behavioral Brain Research: 499: 115941 

Gunnala S, Buhlman L, Jadavji NM* (2025) How Increase Dietary Folic Acid Intake Impact Healthoutcomes through changes in Inflammation, Angiogenesis, and Neurotoxicity. Nutrients: 17: 1286. 

PREPRINT: Gunnala S, Harrison A, Juba A, Ashcraft P, Bottiglieri T, Buhlman LM, Jadavji NM (2024) Over supplementation of folic acid reduces survival 24 hours after hypoxia in male and female Drosophila melanogaster. https://www.biorxiv.org/content/10.1101/2024.10.23.619884v1 

​​24. Sanika Joshi, MBS  – Doctor of Osteopathic Medicine Student (Kenneth Saurez Research Fellow)

Current position: Doctor of Osteopathic Medicine studentt, Midwestern University

Publications:

Joshi SM, McCabe R, Jadavji NM * (2024) Dietary interventions and neurobehavior in society. Nutritional Neuroscience: from bench to bed side. Editor: Reinaldo Oria, Joano Malva, Carlos Alexander Netto. Elsevier. (invited)

Joshi S, Jadavji NM* (2024) Deficiencies in one-carbon metabolism led to increased neurological disease risk and worse outcome: homocysteine is a marker of disease state. Frontiers in Nutrition: 11. 1285502

Joshi S, Currier Thomas T, Jadavji NM* (2024). The impact of increasing one-carbon metabolites on  traumatic brain injury (TBI) outcome using pre-clinical models. Neural Regeneration Research: 19: 1728-33.

23. Abbey McKee, MBS - Doctor of Osteopathic Medicine Student 

Current position: Doctor of Osteopathic Medicine student

Publication

Virdi S, McKee AM, Nuthi M, Jadavji NM* (2023). The role of one-carbon metabolism on healthy brain aging. Nutrients. 15: 3891. (invited).

22. Lilah Manfredi, High School Student Volunteer

Current position: High school student

Publications:

Burrows P, Dhillon H, McDermott GE, Covaleski A, Manfredi L, Beach TG, Serrano GE, Jadavji NM* (2026). Ischemic stroke increases levels of the folate receptor and one-carbon enzymes in male and female brain tissue.Translational Stroke Research, 17:87 

21. Alice Yaldiko,  BS  – Doctor of Osteopathic Medicine Student

Current position: Internal Medicine Resident

Publications

Yaldiko A, Coonrod S, Marella P, Hurley L, Jadavji NM* (2024) Maternal dietary deficiencies in folic acid or choline reduce primary neuron viability after exposure to hypoxia through increased levels of apoptosis. Nutritional Neuroscience: In Press

PREPRINT: Yaldiko A, Coonrod S, Marella P, Hurley L, Jadavji NM. Maternal dietary deficiencies in folic acid or choline reduce primary   neuron viability after exposure to hypoxia through increased levels of apoptosis. https://www.biorxiv.org/content/10.1101/2023.12.09.570894v1

Himmat Dhillon, B.Sc. – Doctor of Osteopathic Medicine Student  

Current position:  Resident Family Medicine Creighton University 

Publications:

Burrows P, Dhillon H, McDermott GE, Covaleski A, Manfredi L, Beach TG, Serrano GE, Jadavji NM* (2026). Ischemic stroke increases levels of the folate receptor and one-carbon enzymes in male and female brain tissue.Translational Stroke Research, 17:87 

20. Kasey Pull, B.A. - Research Assistant

Current position: Teacher

Publications

McCabe RM, Hurley L, Pull K, Jadavji NM* (2026) Immunotherapies for Ischemic Stroke Patients: Current Status and Future Directions. Medical Sciences: 14:111 

PREPRINT: Esfandiarei M, Anwar F, Nuthi M, Harrison A, Barrameda ME, Curry T, Pull K, Currier Thomas T, Jadavji NM (2024) Apoptosis is increased in cortical neurons of female Marfan Syndrome mice. https://www.biorxiv.org/content/10.1101/2024.10.14.618278v1 

Hurley L, Pull K, Jadavji NM (2022) Immunotherapies for Ischemic Stroke. Immunotherapy: Cancer and Beyond. Editors: Deshmukh and Lamichhane. (invited).

Pull K, Folk R, Kang J, Jackson S, Gusek B, Esfandiarei M, Jadavji NM. (2022) Maternal dietary choline deficiencies during pregnancy and lactation reduce cerebral blood flow in 3-month-old female mice offspring following ischemic stroke to the sensorimotor cortex. https://www.biorxiv.org/content/10.1101/2022.08.23.505040v1

Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T, Malysheva O, Caudill M, Jadavji NM. (2023)  Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring, Neural Regeneration Research. 18:2443-2448

PREPRINT: Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T,   Malysheva O, Caudill M, Jadavji NM (2022) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring.  https://www.biorxiv.org/content/10.1101/2022.09.28.509960v1

Hurley L, Jauhal J, Ille S, Pull K, Malysheva OV, Jadavji NM. (2023) Maternal dietary deficiencies in one-carbon metabolism during early neurodevelopment result in larger damage volume, reduced neurodegeneration and neuroinflammation and changes in choline metabolites after ischemic stroke in middle-aged offspring. Nutrients. 15:1556 (Invited)

PREPRINT Hurley L, Jauhal J, Ille S, Pull K, Malysheva OV, Jadavji NM. (2023) Maternal dietary deficiencies in one-carbon metabolism during early neurodevelopment result in larger damage volume, reduced neurodegeneration and neuroinflammation and changes in choline metabolites after ischemic stroke in middle-aged offspring. https://www.biorxiv.org/content/10.1101/2023.02.15.528759v1

Pull K, Folk R, Kang J, Jackson S, Gusek B, Esfandiarei M, Jadavji NM (2023) Maternal dietary choline deficiencies during pregnancy and lactation reduce cerebral blood flow in 3-month-old female mice offspring following ischemic stroke to the sensorimotor cortex. American Journal of Physiology – Heart and Circulatory Physiology: In press

19. Lauren Hurley, B.Sc.- Research Assistant (College of Veterinary Medicine Fellow Summer 2022)

Current position: Veterinary Student, Midwestern University

Publications:

McCabe RM, Hurley L, Pull K, Jadavji NM* (2026) Immunotherapies for Ischemic Stroke Patients: Current Status and Future Directions. Medical Sciences: 14:111 

Yaldiko A, Coonrod S, Marella P, Hurley L, Jadavji NM* (2024) Maternal dietary deficiencies in folic acid or choline reduce primary neuron viability after exposure to hypoxia through increased levels of apoptosis. Nutritional Neuroscience: In Press

PREPRINT: Yaldiko A, Coonrod S, Marella P, Hurley L, Jadavji NM. Maternal dietary deficiencies in folic acid or choline reduce primary   neuron viability after exposure to hypoxia through increased levels of apoptosis. https://www.biorxiv.org/content/10.1101/2023.12.09.570894v1

Hurley L, Pull K, Jadavji NM (2022) Immunotherapies for Ischemic Stroke. Immunotherapy: Cancer and Beyond. Editors: Deshmukh and Lamichhane. (invited).

Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T, Malysheva O, Caudill M, Jadavji NM. (2023) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring, Neural Regeneration Research. 18:2443-2448.

PREPRINT: Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T,   Malysheva O, Caudill M, Jadavji NM (2022) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring.  https://www.biorxiv.org/content/10.1101/2022.09.28.509960v1

Hurley L, Jauhal J, Ille S, Pull K, Malysheva OV, Jadavji NM. (2023) Maternal dietary deficiencies in one-carbon metabolism during early neurodevelopment result in larger damage volume, reduced neurodegeneration and neuroinflammation and changes in choline metabolites after ischemic stroke in middle-aged offspring. Nutrients. 15:1556 (Invited)

PREPRINT: Hurley L, Jauhal J, Ille S, Pull K, Malysheva OV, Jadavji NM. (2023) Maternal dietary deficiencies in one-carbon metabolism during early neurodevelopment result in larger damage volume, reduced neurodegeneration and neuroinflammation and changes in choline metabolites after ischemic stroke in middle-aged offspring. https://www.biorxiv.org/content/10.1101/2023.02.15.528759v1

18. Purvaja Marella, B.S. - Doctor of Osteopathic Medicine Student (Kenneth Saurez Research Fellow)

Current position: Resident Physician University of Minnesota Department of Medicine

Publications:

Yaldiko A, Coonrod S, Marella P, Hurley L, Jadavji NM* (2024) Maternal dietary deficiencies in folic acid or choline reduce primary neuron viability after exposure to hypoxia through increased levels of apoptosis. Nutritional Neuroscience: In Press

PREPRINT: Yaldiko A, Coonrod S, Marella P, Hurley L, Jadavji NM. Maternal dietary deficiencies in folic acid or choline reduce primary   neuron viability after exposure to hypoxia through increased levels of apoptosis. https://www.biorxiv.org/content/10.1101/2023.12.09.570894v1

Marella P, Yahn GB, Kang J, Jadavji NM. (2022) The impact of homocysteine on ischemic stroke and dementia:    an updated review of clinical studies and mechanisms in Advances in Health and Disease. Nova Science Publishers Inc. 

Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T, Malysheva O, Caudill M, Jadavji NM. (2023) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring, Neural Regeneration Research. 18:2443-2448.

PREPRINT: Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T,   Malysheva O, Caudill M, Jadavji NM (2022) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring.  https://www.biorxiv.org/content/10.1101/2022.09.28.509960v1

17. Gyllian Yahn, MBS - Master of Biomedical Science and Doctor of Dental Medicine Student

Current position: Dental Student, Midwestern University

Publications:

Yahn GB, Abato JE, Jadavji NM (2021) Role of vitamin B12 deficiency in ischemic stroke risk and outcome. Neural Regen Res 16(3):470-474. ​

Yahn GB, Leoncio J, Jadavji NM (2021) The role of dietary supplementation of one-carbon metabolism on stroke outcome. Current Opinion in Clinical Nutrition and Metabolic Care: doi: 10.1097/MCO.0000000000000743 (invited)

Yahn GB, Wasek B, Bottiglieri T,  Malysheva O, Caudill MA, Jadavji NM. (2021) A dietary vitamin B12 deficiency impairs motor function and changes neuronal survival and choline metabolism after ischemic stroke to the sensorimotor cortex in middle aged male and female mice. https://www.biorxiv.org/content/10.1101/2021.08.17.456684v3

Marella P, Yahn GB, Kang J, Jadavji NM. (2022) The impact of homocysteine on ischemic stroke and dementia: an updated review of clinical studies and mechanisms in Advances in Health and Disease. Nova Science Publishers Inc.

Yahn GB, Wasek B, Bottiglieri T, Malysheva O, Caudill MA, Jadavji NM (2023) A dietary vitamin B12 deficiency impairs motor function and changes neuronal survival and choline metabolism after ischemic stroke to the sensorimotor cortex in middle aged male and female mice. Nutritional Neuroscience, In Press https://doi.org/10.1080/1028415X.2023.2188639.

16. Sapna Viridi, MBS - Doctor of Osteopathic Medicine Student

Current position: Doctor of Osteopathic Medicine student, Midwestern University

Publications:

Virdi S, Jadavji NM* (2022) The impact of maternal folates on brain development and function after birth. Metabolites. 12(9): 876. (invited)

Virdi S, McKee AM, Nuthi M, Jadavji NM* (2023). The role of one-carbon metabolism on healthy brain aging. Nutrients. 15: 3891. (invited)

15. Jesse Jauhal, B.S. - Master of Biomedical Sciences Student

Current position: Dental Student, Midwestern University

 Publication:

Clementson M, Jauhal J, Jadavji NM (2023) Dietary B-vitamins deficiencies and maternal over supplementation on neurodevelopment: an updated narrative. Vitamins and Minerals in Neurological Disorders. Editor: Colin Martin, Vinood Patel, and Victor Preedy. Elsevier. p661-672. (invited).

Clementson M, Jauhal J, Jadavji NM (2023) Dietary B-vitamins deficiencies and maternal over supplementation on neurodevelopment: an updated narrative. Vitamins and Minerals in Neurological Disorders. Editor: Colin Martin, Vinood Patel, and Victor Preedy. Elsevier. (invited).

PREPRINT Hurley L, Jauhal J, Ille S, Pull K, Malysheva OV, Jadavji NM. (2023) Maternal dietary deficiencies in one-carbon metabolism during early neurodevelopment result in larger damage volume, reduced neurodegeneration and neuroinflammation and changes in choline metabolites after ischemic stroke in middle-aged offspring. https://www.biorxiv.org/content/10.1101/2023.02.15.528759v1

14. Jeemin Kang, MA - Doctor of Osteopathic Medicine Student

Current position: Medical Student, Midwestern University

Publications:

Marella P, Yahn GB, Kang J, Jadavji NM. (2022) The impact of homocysteine on ischemic stroke and dementia: an   updated review of clinical studies and mechanisms in Advances in Health and Disease. Nova Science Publishers Inc.

Pull K, Folk R, Kang J, Jackson S, Gusek B, Esfandiarei M, Jadavji NM. (2022) Maternal dietary choline deficiencies during pregnancy and lactation reduce cerebral blood flow in 3-month-old female mice offspring following ischemic stroke to the sensorimotor cortex. https://www.biorxiv.org/content/10.1101/2022.08.23.505040v1

Pull K, Folk R, Kang J, Jackson S, Gusek B, Esfandiarei M, Jadavji NM (2023) Maternal dietary choline deficiencies during pregnancy and lactation reduce cerebral blood flow in 3-month-old female mice offspring following ischemic stroke to the sensorimotor cortex. American Journal of Physiology – Heart and Circulatory Physiology: In press 

13. Sarah Coonrod, BSc. - College Veterinary Medicine Fellow, Summer 2021

Current position: Veterinary Student

Publications

PREPRINT: Yaldiko A, Coonrod S, Marella P, Hurley L, Jadavji NM. Maternal dietary deficiencies in folic acid or choline reduce primary   neuron viability after exposure to hypoxia through increased levels of apoptosis. https://www.biorxiv.org/content/10.1101/2023.12.09.570894v1

Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T, Malysheva O, Caudill M, Jadavji NM. (2023) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring, Neural Regeneration Research. 18:2443-2448.

PREPRINT: Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T,   Malysheva O, Caudill M, Jadavji NM (2022) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring.  https://www.biorxiv.org/content/10.1101/2022.09.28.509960v1

12. Agnes S. Pascual, M.S. – Senior Research Specialist

Publications:     

Poole J, Jasbi J, Pascual AS, North S, Kwatra N, Weissig V, Gu H, Bottiglieri T, Jadavji NM. (2022) Ischemic stroke and dietary vitamin B12 deficiency in old-aged females impaired motor function, increased ischemic damage size, and changed metabolite profiles in brain and cecum tissue. Nutrients, 14(14), 2960; https://doi.org/10.3390/nu14142960

PREPRINT: Poole J, Jasbi J, Pascual AS, North S, Kwatra N, Weissig V, Gu H, Bottiglieri T, Jadavji NM. Ischemic stroke and dietary vitamin B12 deficiency in old-aged females impaired motor function, increased ischemic damage size, and changed metabolite profiles in brain and cecum tissue. https://www.biorxiv.org/content/10.1101/2022.04.04.487028v2

Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T, Malysheva O, Caudill M, Jadavji NM. (2023) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring, Neural Regeneration Research. 18:2443-2448.

PREPRINT: Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T,   Malysheva O, Caudill M, Jadavji NM (2022) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring.  https://www.biorxiv.org/content/10.1101/2022.09.28.509960

11. McCoy  Clementson, B.S. - Doctor of Osteopathic Medicine Student
(Kenneth Saurez Research Fellow)

Current position: Emergency Medicine Resident

Publications:

Clementson M, Jauhal J, Jadavji NM (2023) Dietary B-vitamins deficiencies and maternal over supplementation on neurodevelopment: an updated narrative. Vitamins and Minerals in Neurological Disorders. Editor: Colin Martin, Vinood Patel, and Victor Preedy. Elsevier. (invited).

Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T, Malysheva O, Caudill M, Jadavji NM. (2023) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring, Neural Regeneration Research. 18:2443-2448.

PREPRINT: Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T,   Malysheva O, Caudill M, Jadavji NM (2022) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring.  https://www.biorxiv.org/content/10.1101/2022.09.28.509960v1

10. Joshua Poole, B.S. - Doctor of Osteopathic Medicine Student (Kenneth Saurez Research Fellow)

Current position: Anesthesia Resident at UT Houston

Publications:    

Poole J, Jasbi J, Pascual AS, North S, Kwatra N, Weissig V, Gu H, Bottiglieri T, Jadavji NM. (2022) Ischemic stroke and dietary vitamin B12 deficiency in old-aged females impaired motor function, increased ischemic damage size, and changed metabolite profiles in brain and cecum tissue. Nutrients, 14(14), 2960; https://doi.org/10.3390/nu14142960

PREPRINT: Poole J, Jasbi J, Pascual AS, North S, Kwatra N, Weissig V, Gu H, Bottiglieri T, Jadavji NM. (2022) Ischemic stroke and dietary vitamin B12 deficiency in old-aged females impaired motor function, increased ischemic damage size, and changed metabolite profiles in brain and cecum tissue. https://www.biorxiv.org/content/10.1101/2022.04.04.487028v2

​9. Shaley Jackson, B.Sc. - Research Assistant​

Current position: Veterinary student, Midwestern University

Publications:

Pull K, Folk R, Kang J, Jackson S, Gusek B, Esfandiarei M, Jadavji NM. (2022) Maternal dietary choline deficiencies       during pregnancy and lactation reduce cerebral blood flow in 3-month-old female mice offspring following ischemic stroke to the sensorimotor cortex. https://www.biorxiv.org/content/10.1101/2022.08.23.505040v1

Pull K, Folk R, Kang J, Jackson S, Gusek B, Esfandiarei M, Jadavji NM (2023) Maternal dietary choline deficiencies during pregnancy and lactation reduce cerebral blood flow in 3-month-old female mice offspring following ischemic stroke to the sensorimotor cortex. American Journal of Physiology – Heart and Circulatory Physiology: In press

​8. Sean North, B.Sc. - Research Assistant

Current position: Medical student, Midwestern University

Publications 

Poole J, Jasbi J, Pascual AS, North S, Kwatra N, Weissig V, Gu H, Bottiglieri T, Jadavji NM. (2022) Ischemic stroke and dietary vitamin B12 deficiency in old-aged females impaired motor function, increased ischemic damage size, and changed metabolite profiles in brain and cecum tissue. Nutrients, 14(14), 2960; https://doi.org/10.3390/nu14142960

PREPRINT: Poole J, Jasbi J, Pascual AS, North S, Kwatra N, Weissig V, Gu H, Bottiglieri T, Jadavji NM. Ischemic stroke and dietary vitamin B12 deficiency in old-aged females impaired motor function, increased ischemic damage size, and changed metabolite profiles in brain and cecum tissue. https://www.biorxiv.org/content/10.1101/2022.04.04.487028v2

7. Neha Kwatra, B.Sc. - Research Assistant

Current position: Dentist and Captain in the US Air Force

Publications: 

Kwarta N, Jadavji NM. (2020) How changes in our genes impact outcome after stroke. Atlas of Science. https://atlasofscience.org/how-changes-in-our-genes-impact-outcome-after-stroke/

Burgess K, Bennett C, Mosnier H, Kwatra N, Bethel B, Jadavji NM (2020) The antioxidant role of one-carbon metabolism on stroke. Antioxidants. 9(11):1141 (invited​)

Bennett C, Green J, Ciancio M, Goral J, Pitstick L, Pytynia M, Meyer A, Kwatra N, Jadavji NM*. (2021) Dietary folic acid deficiency impacts hippocampal morphology and cortical acetylcholine metabolism in adult male and female mice. Nutritional Neuroscience: In Press

Poole J, Jasbi J, Pascual AS, North S, Kwatra N, Weissig V, Gu H, Bottiglieri T, Jadavji NM. Ischemic stroke and dietary vitamin B12 deficiency in old-aged females impaired motor function, increased ischemic damage size, and changed metabolite profiles in brain and cecum tissue. https://www.biorxiv.org/content/10.1101/2022.04.04.487028v2

Poole J, Jasbi J, Pascual AS, North S, Kwarta N, Weissig V, Gu H, Bottiglieri T, Jadavji NM. (2022) Ischemic stroke and dietary vitamin B12 deficiency in old-aged females impaired motor function, increased ischemic damage size, and changed metabolite profiles in brain and cecum tissue. Nutrients, 14(14), 2960; https://doi.org/10.3390/nu14142960

6. Jeannine Leoncio, B.S. - Research Assistant

Current Position: Pharmacy Student, Midwestern University

Publication: 

Yahn GB, Leoncio J, Jadavji NM The role of dietary supplementation of one-carbon metabolism on stroke outcome. Current Opinion in Clinical Nutrition and Metabolic Care: doi: 10.1097/MCO.0000000000000743 (invited)

5. ​Calli Bennett, B.Sc. - Doctor of Osteopathic Medicine Student (Kenneth Saurez Research Fellow)

Current position: OBGYN Resident

Publications

Burgess K, Bennett C, Mosnier H, Kwatra N, Bethel B, Jadavji NM (2020) The antioxidant role of one-carbon  metabolism on stroke. Antioxidants. 9(11):1141  (invited)

Bennett C, Green J, Ciancio M, Goral J, Pitstick L, Pytynia M, Meyer A, Kwatra N, Jadavji NM*. (2021) Dietaryfolic acid deficiency impacts hippocampal morphology and cortical acetylcholine metabolism in adult male and female mice. Nutritional Neuroscience: In Press

Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T, Malysheva O, Caudill M, Jadavji NM. (2023) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring, Neural Regeneration Research. 18:2443-2448.

PREPRINT: Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T,     Malysheva O, Caudill M, Jadavji NM (2022) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring.  https://www.biorxiv.org/content/10.1101/2022.09.28.509960v1

4. Kassidy Burgess, BS -  College of Veterinary Medicine Fellow 

Current Position: Associate Veterinarian at Lakefield Veterinary Group 

Publications

Burgess K, Bennett C, Mosnier H, Kwatra N, Bethel B, Jadavji NM. (2020) The antioxidant role of one- carbon metabolism on stroke. Antioxidants. 9(11):1141 (invited)

3. Forrest Bethel, MSc - Doctor of Osteopathic Medicine Student (Kenneth Saurez Research Fellow)

Current position: Surgery Resident

Publication

Burgess K, Bennett C, Mosnier H, Kwatra N, Bethel B, ​ Jadavji NM. (2020) The antioxidant role of one-carbon metabolism on stroke. Antioxidants. 9(11):1141  (invited)

2. Chelsea Adamson, MPH  – Research Assistant    

Current position:  Supervisor of Molecular Operations, Solid Tumor at Caris Life Sciences      

Publication

Al Rubaye H, Adamson C, Jadavji NM (2020) The role of maternal diet on offspring gut microbiota development. Journal of Neuroscience Research. PMID: 32112450

1. Jamie Abato, BSc - Research Assistant

Current position: Veterinary Technician, Basking Ridge Animal Hospital

Publications

Abato JE, Moftah M, Cron GO, Smith PD, Jadavji NM*. (2020) Methylenetetrahydrofolate reductase deficiency alters cellular response after ischemic stroke in male mice. Nutritional Neuroscience. http://dx.doi.org/10.1080/1028415X.2020.1769412. 

Yahn GB, Abato JE, Jadavji NM (2021) Role of vitamin B12 deficiency in ischemic stroke risk and outcome. Neural Regen Res 16(3):470-474. ​


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