Link to Dr. Jadavji's CV
Dr. Nafisa (n uh - f ee - s ah) M. Jadavji (j aa - d uh v - j ee) is a Neuroscientist and mother. She is an Assistant Professor at Southern Illinois University Carbondale. She completed her doctoral training at McGill University in Montréal, Canada.
The Jadavji laboratory investigates how the brain responds to different biological processes throughout the lifespan. More specifically, her laboratory studies how the brain responds to changes in one-carbon metabolism, with a specific focus on maternal nutrition contributions to offspring neurodevelopment, neurological diseases (e.g. ischemic stroke and vascular dementia), and aging.
Her lab has contributed to the neuroscience aging research including providing an understanding on how dietary deficiencies in vitamin B12 increase apoptosis in brain tissue and change mitochondria metabolites within the gut after an ischemic stroke. They have also shown that a maternal diet deficient in either choline or folic acid during pregnancy negatively impacts ischemic stroke outcome in male and female offspring. This work has focused on behavioral outcomes, brain tissue analysis, stool metabolites, and blood flow within the brain.
Dr. Jadavji has received funding from the US Department of Agriculture (USDA), National Institutes of Health – NINDS (US), Arizona Department of Health, American Heart Association (US), Federation of European Neuroscience Society (Europe), NeuroWIND (Germany), Canadian Association for Neuroscience, Canadian Institutes of Health Research, National Science & Engineering Research Council (Canada), International Brain Research Organization, Parkinson's disease Foundation (US), Burroughs Wellcome Fund (US) and Fonds de la recherché en santé Québec (Canada).
Dr. Jadavji’s research has been published in Biochemical Journal, Neuroendocrinology, Experimental Neurology, Journal of Neuroscience, Human Molecular Genetics, Nutrition Reviews, Toxicological Science, European Journal of Neuroscience, Neural Regeneration Research, Nutritional Neuroscience, Nutrients, and Neurobiology of Disease. Dr. Jadavji has published 75 peer reviewed papers, over 150 abstracts, and given 60 invited talks about the research conducted in her laboratory. She has also posted several preprints.
Dr. Jadavji is an Editorial member at Scientific Reports, Bioprotocols, Metabolites, Nutrients, and Journal of Stroke and Cerebrovascular Diseases journals. She is the Chair of the Board of Directors for the Journal of Young Investigators (JYI) and Chair of the Advisory Board for Reproducibility for Everyone (R4E).
Dr. Jadavji has supervised and mentored over 80 undergraduate, graduate, and postdocs so far during her scientific career.
When she is not in the laboratory, teaching, or writing, Dr. Jadavji enjoys exercising, cooking, and baking gluten free treats. She is also an avid traveler and knitter.
My name is Elijah Neitzel, and I am currently a sophomore at Southern Illinois University Carbondale. I am majoring in Biology and minoring in Chemistry. In the future, I hope to attend medical school and wish to become an emergency physician. I am very excited, and interested in working for the Jadavji Laboratory! Learning more about neuroscience and the brain is one of my favorite things to do. In my free time, I like to lift weights, play music, hang out with friends, and read
Awards:
- 2026-27 Susan C. Thrasher Undergraduate Research Fund
- 2026 Journal of Young Investigator Grant
Abell AJ, Schuler LK, Jadavji NM* (2026). Maternal dietary intake of folic acid, vitamin B12, and choline impacts offspring DNA methylation after birth. Nutrients, 18: 3306. *Featured on cover of Nutrients October 2026
Awards:
2026-27 Research-Enriched Academic Challenge Award
Jadavji Laboratory Alumni
41. Alek Abell, BS - Biomedical Sciences Undergraduate Student
Publication:
Abell AJ, Schuler LK, Jadavji NM* (2026). Maternal dietary intake of folic acid, vitamin B12, and choline impacts offspring DNA methylation after birth. Nutrients, 18: 3306. *Featured on cover of Nutrients October 2026
Award:
2025 Journal of Young Investigator Grant
40. Farwah Wasiq, BS - SIU SOM MPEE Student
Current Position: SOM Medical Student
39. Nora Jones - Biomedical Sciences Undergraduate Student
Publications:
Jones N, Binte S, Jadavji NM* (2026) Highlighting the mechanisms through which increased dietary folic acid and choline impact regeneration in the brain after damage. Neural Regeneration:21. doi: 10.4103/NRR.NRR-D-25-01911
Award:
2025 Journal of Young Investigator Grant
38. Elizabeth Pineda
Award
2026 Journal of Young Investigator Grant
37. Riley McCabe - Physiology Undergraduate Student
Current Position: Physiology Undergraduate Student
Publication:
Joshi SM, McCabe R, Jadavji NM * (2024) Dietary interventions and neurobehavior in society. Nutritional Neuroscience: from bench to bed side. Editor: Reinaldo Oria, Joano Malva, Carlos Alexander Netto. Elsevier. (invited)
McCabe RM, Hurley L, Pull K, Jadavji NM* (2026) Immunotherapies for Ischemic Stroke Patients: Current Status and Future Directions. Medical Sciences: 14:111
36. Gillian McDermott - SIU SOM MPEE Student
Current Position: SOM Medical Student
Publications:
Burrows P, Dhillon H, McDermott GE, Covaleski A, Manfredi L, Beach TG, Serrano GE, Jadavji NM* (2026). Ischemic stroke increases levels of the folate receptor and one-carbon enzymes in male and female brain tissue.Translational Stroke Research, 17:87
35. Meher Garg - High school SIU STEM Program Student, 2025 and 2026
Current position: High School Student
Award: Florence M. Foote Scholarship
33. Kalysta Conley - Physiology Undergraduate student
Current position: Physican Assistant Student
Gunther Strash, M.B.S, – College of Osteopathic Medicine
Current position: Doctor of Osteopathic Medicine student, Midwestern University
Publications:
Esfandiarei M, Strash SGU, Covaleski A, Ille S, Li W, Jadavji NM* (2024) Maternal dietary deficiency in choline reduced levels of MMP-2 levels in blood and brain tissue of male offspring mice. Cells: 13.1472
PREPRINT: Esfandiarei M, Strash SGU, Covaleski A, Ille S, Li W, Jadavji NM* (2024) Maternal dietary deficiency in choline reduced levels of MMP-2 levels in blood and brain tissue of male offspring mice. https://www.biorxiv.org/content/10.1101/2024.07.15.603575v1
32. Alisha Harrison, BA – Sr. Research Specialist, Midwestern University
Current position: Senior Research Specialist
Publications:
Esfandiarei M, Anwar F, Nuthi M, Harrison A, Barrameda ME, Curry T, Pull K, Currier Thomas T, Jadavji NM (2025) Apoptosis is increased in cortical neurons of female Marfan Syndrome mice. microPublication Biology. 10.17912/micropub.biology.001651. PMID: 40896254.
Gunnala S, Harrison A, Juba A, Ashcraft P, Garg M, Bottiglieri T, Buhlman LM, Jadavji NM* (2026) Increased dietary levels of folic acid reduce survival and alters climbing behaviors 24 hours after hypoxia in male and female Drosophila melanogaster. Behavioral Brain Research: 499: 115941
PREPRINT: Gunnala S, Harrison A, Juba A, Ashcraft P, Bottiglieri T, Buhlman LM, Jadavji NM (2024) Over supplementation of folic acid reduces survival 24 hours after hypoxia in male and female Drosophila melanogaster. https://www.biorxiv.org/content/10.1101/2024.10.23.619884v1
PREPRINT: Esfandiarei M, Anwar F, Nuthi M, Harrison A, Barrameda ME, Curry T, Pull K, Currier Thomas T, Jadavji NM (2024) Apoptosis is increased in cortical neurons of female Marfan Syndrome mice. https://www.biorxiv.org/content/10.1101/2024.10.14.618278v1
31. Mary-Tyler Mosley - Undergraduate Student
Current position: Undergraduate Student, Stanford University
Publications
Anwar F, Mosely MT, Jasbi P, Chi J, Gu H, Jadavji NM* (2024) Maternal dietary deficiencies in folic acid and choline change metabolites levels in offspring after ischemic stroke. Metabolites: 14.552.
PREPRINT: Anwar F, Mosely MT, Jasbi P, Chi J, Gu H, Jadavji NM (2024) Maternal dietary deficiencies in folic acid and choline change metabolites levels in offspring after ischemic stroke. https://www.biorxiv.org/content/10.1101/2024.06.29.601358v2.full.pdf+html
30. Sharadyn Ille, B.S. – Doctor of Dental Medicine Student
Current position: Resident, Periodontics, Western Virginia University
Publications:
Esfandiarei M, Strash SGU, Covaleski A, Ille S, Li W, Jadavji NM* (2024) Maternal dietary deficiency in choline reduced levels of MMP-2 levels in blood and brain tissue of male offspring mice. Cells: 13.1472
PREPRINT: Esfandiarei M, Strash SGU, Covaleski A, Ille S, Li W, Jadavji NM* (2024) Maternal dietary deficiency in choline reduced levels of MMP-2 levels in blood and brain tissue of male offspring mice. https://www.biorxiv.org/content/10.1101/2024.07.15.603575v1
Hurley L, Jauhal J, Ille S, Pull K, Malysheva OV, Jadavji NM. (2023). Maternal dietary deficiencies in one-carbon metabolism during early neurodevelopment result in larger damage volume, reduced neurodegeneration and neuroinflammation and changes in choline metabolites after ischemic stroke in middle-aged offspring. Nutrients. 15:1556 (Invited)
PREPRINT Hurley L, Jauhal J, Ille S, Pull K, Malysheva OV, Jadavji NM. (2023) Maternal dietary deficiencies in one-carbon metabolism during early neurodevelopment result in larger damage volume, reduced neurodegeneration and neuroinflammation and changes in choline metabolites after ischemic stroke in middle-aged offspring. https://www.biorxiv.org/content/10.1101/2023.02.15.528759v1
29. Faizan Anwar, BS – College of Osteopathic Medicine
Current position: Doctor of Osteopathic Medicine student, Midwestern University
Publications
Esfandiarei M, Anwar F, Nuthi M, Harrison, Barrameda ME, Curry T, Pull K, Currier Thomas T, Jadavji NM (2025) Apoptosis is increased in cortical neurons of female Marfan Syndrome mice. microPublication Biology. 10.17912/micropub.biology.001651. PMID: 40896254.
PREPRINT: Esfandiarei M, Anwar F, Nuthi M, Harrison A, Barrameda ME, Curry T, Pull K, Currier Thomas T, Jadavji NM (2024) Apoptosis is increased in cortical neurons of female Marfan Syndrome mice. https://www.biorxiv.org/content/10.1101/2024.10.14.618278v1
Anwar F, Mosely MT, Jasbi P, Chi J, Gu H, Jadavji NM* (2024) Maternal dietary deficiencies in folic acid and choline change metabolites levels in offspring after ischemic stroke. Metabolites: 14.552.
PREPRINT: Anwar F, Mosely MT, Jasbi P, Chi J, Gu H, Jadavji NM (2024) Maternal dietary deficiencies in folic acid and choline change metabolites levels in offspring after ischemic stroke. https://www.biorxiv.org/content/10.1101/2024.06.29.601358v2.full.pdf+html
28. Manogna Nuthi, BS - College of Osteopathic Medicine
Current position: Doctor of Osteopathic Medicine student, Midwestern University
Publications
Esfandiarei M, Anwar F, Nuthi M, Harrison, Barrameda ME, Curry T, Pull K, Currier Thomas T, Jadavji NM (2025) Apoptosis is increased in cortical neurons of female Marfan Syndrome mice. microPublication Biology. 10.17912/micropub.biology.001651. PMID: 40896254.
PREPRINT: Esfandiarei M, Anwar F, Nuthi M, Harrison A, Barrameda ME, Curry T, Pull K, Currier Thomas T, Jadavji NM (2024) Apoptosis is increased in cortical neurons of female Marfan Syndrome mice. https://www.biorxiv.org/content/10.1101/2024.10.14.618278v1
Virdi S, McKee AM, Nuthi M, Jadavji NM* (2023). The role of one-carbon metabolism on healthy brain aging. Nutrients. 15: 3891. (IF =5.9) (invited)
27. Amanda Covaleski, B.S. – College of Pharmacy
Current position: Resident at VA Tennessee Valley
Publications:
Esfandiarei M, Strash SGU, Covaleski A, Ille S, Li W, Jadavji NM* (2024) Maternal dietary deficiency in choline reduced levels of MMP-2 levels in blood and brain tissue of male offspring mice. Cells: 13.1472
PREPRINT: Esfandiarei M, Strash SGU, Covaleski A, Ille S, Li W, Jadavji NM* (2024) Maternal dietary deficiency in choline reduced levels of MMP-2 levels in blood and brain tissue of male offspring mice. https://www.biorxiv.org/content/10.1101/2024.07.15.603575v1
Burrows P, Dhillon H, McDermott GE, Covaleski A, Manfredi L, Beach TG, Serrano GE, Jadavji NM* (2026). Ischemic stroke increases levels of the folate receptor and one-carbon enzymes in male and female brain tissue.Translational Stroke Research, 17:87
26. Brooklynn Flynn, BSc - College of Osteopathic Medicine
Current position: Doctor of Osteopathic Medicine student, Midwestern University
Publications:
Flynn B, Cheng L, Hagan A, Kozik AJ, Ng J, Smith CT, Haage A, Jadavji NM* (2024). An updated and expanded characterization of the biological sciences academic job market. Frontiers in Research Metrics and Analytics: In press
Petter Burrows, B.S. - College of Veterinary Medicine Fellow 2023
Current position: Small Animal Rotating Intern Department of Clinical Sciences Tufts University
Publications:
Burrows P, Dhillon H, McDermott GE, Covaleski A, Manfredi L, Beach TG, Serrano GE, Jadavji NM* (2026). Ischemic stroke increases levels of the folate receptor and one-carbon enzymes in male and female brain tissue.Translational Stroke Research, 17:87
25. Siddarth Gunnala, MBS - Master of Biomedical Science and Doctor of Osteopathic Medicine Student
Current position: Doctor of Osteopathic Medicine student, Midwestern University
Publications:
Gunnala S, Jadavji NM* (2026) Climbing Behavior of Drosophila melanogaster Larvae in Response to Hypoxia.Journal of Visualized Experiments: Encyclopedia of Experiments: 208.
Gunnala S, Harrison A, Juba A, Ashcraft P, Garg M, Bottiglieri T, Buhlman LM, Jadavji NM* (2026) Increased dietary levels of folic acid reduce survival and alters climbing behaviors 24 hours after hypoxia in male and female Drosophila melanogaster. Behavioral Brain Research: 499: 115941
Gunnala S, Buhlman L, Jadavji NM* (2025) How Increase Dietary Folic Acid Intake Impact Healthoutcomes through changes in Inflammation, Angiogenesis, and Neurotoxicity. Nutrients: 17: 1286.
PREPRINT: Gunnala S, Harrison A, Juba A, Ashcraft P, Bottiglieri T, Buhlman LM, Jadavji NM (2024) Over supplementation of folic acid reduces survival 24 hours after hypoxia in male and female Drosophila melanogaster. https://www.biorxiv.org/content/10.1101/2024.10.23.619884v1
24. Sanika Joshi, MBS – Doctor of Osteopathic Medicine Student (Kenneth Saurez Research Fellow)
Current position: Doctor of Osteopathic Medicine studentt, Midwestern University
Publications:
Joshi SM, McCabe R, Jadavji NM * (2024) Dietary interventions and neurobehavior in society. Nutritional Neuroscience: from bench to bed side. Editor: Reinaldo Oria, Joano Malva, Carlos Alexander Netto. Elsevier. (invited)
Joshi S, Jadavji NM* (2024) Deficiencies in one-carbon metabolism led to increased neurological disease risk and worse outcome: homocysteine is a marker of disease state. Frontiers in Nutrition: 11. 1285502
Joshi S, Currier Thomas T, Jadavji NM* (2024). The impact of increasing one-carbon metabolites on traumatic brain injury (TBI) outcome using pre-clinical models. Neural Regeneration Research: 19: 1728-33.
23. Abbey McKee, MBS - Doctor of Osteopathic Medicine Student
Current position: Doctor of Osteopathic Medicine student
Publication
Virdi S, McKee AM, Nuthi M, Jadavji NM* (2023). The role of one-carbon metabolism on healthy brain aging. Nutrients. 15: 3891. (invited).
22. Lilah Manfredi, High School Student Volunteer
Current position: High school student
Publications:
Burrows P, Dhillon H, McDermott GE, Covaleski A, Manfredi L, Beach TG, Serrano GE, Jadavji NM* (2026). Ischemic stroke increases levels of the folate receptor and one-carbon enzymes in male and female brain tissue.Translational Stroke Research, 17:87
21. Alice Yaldiko, BS – Doctor of Osteopathic Medicine Student
Current position: Internal Medicine Resident
Publications
Yaldiko A, Coonrod S, Marella P, Hurley L, Jadavji NM* (2024) Maternal dietary deficiencies in folic acid or choline reduce primary neuron viability after exposure to hypoxia through increased levels of apoptosis. Nutritional Neuroscience: In Press
PREPRINT: Yaldiko A, Coonrod S, Marella P, Hurley L, Jadavji NM. Maternal dietary deficiencies in folic acid or choline reduce primary neuron viability after exposure to hypoxia through increased levels of apoptosis. https://www.biorxiv.org/content/10.1101/2023.12.09.570894v1
Himmat Dhillon, B.Sc. – Doctor of Osteopathic Medicine Student
Current position: Resident Family Medicine Creighton University
Publications:
Burrows P, Dhillon H, McDermott GE, Covaleski A, Manfredi L, Beach TG, Serrano GE, Jadavji NM* (2026). Ischemic stroke increases levels of the folate receptor and one-carbon enzymes in male and female brain tissue.Translational Stroke Research, 17:87
20. Kasey Pull, B.A. - Research Assistant
Current position: Teacher
Publications
McCabe RM, Hurley L, Pull K, Jadavji NM* (2026) Immunotherapies for Ischemic Stroke Patients: Current Status and Future Directions. Medical Sciences: 14:111
PREPRINT: Esfandiarei M, Anwar F, Nuthi M, Harrison A, Barrameda ME, Curry T, Pull K, Currier Thomas T, Jadavji NM (2024) Apoptosis is increased in cortical neurons of female Marfan Syndrome mice. https://www.biorxiv.org/content/10.1101/2024.10.14.618278v1
Hurley L, Pull K, Jadavji NM (2022) Immunotherapies for Ischemic Stroke. Immunotherapy: Cancer and Beyond. Editors: Deshmukh and Lamichhane. (invited).
Pull K, Folk R, Kang J, Jackson S, Gusek B, Esfandiarei M, Jadavji NM. (2022) Maternal dietary choline deficiencies during pregnancy and lactation reduce cerebral blood flow in 3-month-old female mice offspring following ischemic stroke to the sensorimotor cortex. https://www.biorxiv.org/content/10.1101/2022.08.23.505040v1
Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T, Malysheva O, Caudill M, Jadavji NM. (2023) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring, Neural Regeneration Research. 18:2443-2448
PREPRINT: Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T, Malysheva O, Caudill M, Jadavji NM (2022) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring. https://www.biorxiv.org/content/10.1101/2022.09.28.509960v1
Hurley L, Jauhal J, Ille S, Pull K, Malysheva OV, Jadavji NM. (2023) Maternal dietary deficiencies in one-carbon metabolism during early neurodevelopment result in larger damage volume, reduced neurodegeneration and neuroinflammation and changes in choline metabolites after ischemic stroke in middle-aged offspring. Nutrients. 15:1556 (Invited)
PREPRINT Hurley L, Jauhal J, Ille S, Pull K, Malysheva OV, Jadavji NM. (2023) Maternal dietary deficiencies in one-carbon metabolism during early neurodevelopment result in larger damage volume, reduced neurodegeneration and neuroinflammation and changes in choline metabolites after ischemic stroke in middle-aged offspring. https://www.biorxiv.org/content/10.1101/2023.02.15.528759v1
Pull K, Folk R, Kang J, Jackson S, Gusek B, Esfandiarei M, Jadavji NM (2023) Maternal dietary choline deficiencies during pregnancy and lactation reduce cerebral blood flow in 3-month-old female mice offspring following ischemic stroke to the sensorimotor cortex. American Journal of Physiology – Heart and Circulatory Physiology: In press
19. Lauren Hurley, B.Sc.- Research Assistant (College of Veterinary Medicine Fellow Summer 2022)
Current position: Veterinary Student, Midwestern University
Publications:
McCabe RM, Hurley L, Pull K, Jadavji NM* (2026) Immunotherapies for Ischemic Stroke Patients: Current Status and Future Directions. Medical Sciences: 14:111
Yaldiko A, Coonrod S, Marella P, Hurley L, Jadavji NM* (2024) Maternal dietary deficiencies in folic acid or choline reduce primary neuron viability after exposure to hypoxia through increased levels of apoptosis. Nutritional Neuroscience: In Press
PREPRINT: Yaldiko A, Coonrod S, Marella P, Hurley L, Jadavji NM. Maternal dietary deficiencies in folic acid or choline reduce primary neuron viability after exposure to hypoxia through increased levels of apoptosis. https://www.biorxiv.org/content/10.1101/2023.12.09.570894v1
Hurley L, Pull K, Jadavji NM (2022) Immunotherapies for Ischemic Stroke. Immunotherapy: Cancer and Beyond. Editors: Deshmukh and Lamichhane. (invited).
Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T, Malysheva O, Caudill M, Jadavji NM. (2023) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring, Neural Regeneration Research. 18:2443-2448.
PREPRINT: Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T, Malysheva O, Caudill M, Jadavji NM (2022) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring. https://www.biorxiv.org/content/10.1101/2022.09.28.509960v1
Hurley L, Jauhal J, Ille S, Pull K, Malysheva OV, Jadavji NM. (2023) Maternal dietary deficiencies in one-carbon metabolism during early neurodevelopment result in larger damage volume, reduced neurodegeneration and neuroinflammation and changes in choline metabolites after ischemic stroke in middle-aged offspring. Nutrients. 15:1556 (Invited)
PREPRINT: Hurley L, Jauhal J, Ille S, Pull K, Malysheva OV, Jadavji NM. (2023) Maternal dietary deficiencies in one-carbon metabolism during early neurodevelopment result in larger damage volume, reduced neurodegeneration and neuroinflammation and changes in choline metabolites after ischemic stroke in middle-aged offspring. https://www.biorxiv.org/content/10.1101/2023.02.15.528759v1
18. Purvaja Marella, B.S. - Doctor of Osteopathic Medicine Student (Kenneth Saurez Research Fellow)
Current position: Resident Physician University of Minnesota Department of Medicine
Publications:
Yaldiko A, Coonrod S, Marella P, Hurley L, Jadavji NM* (2024) Maternal dietary deficiencies in folic acid or choline reduce primary neuron viability after exposure to hypoxia through increased levels of apoptosis. Nutritional Neuroscience: In Press
PREPRINT: Yaldiko A, Coonrod S, Marella P, Hurley L, Jadavji NM. Maternal dietary deficiencies in folic acid or choline reduce primary neuron viability after exposure to hypoxia through increased levels of apoptosis. https://www.biorxiv.org/content/10.1101/2023.12.09.570894v1
Marella P, Yahn GB, Kang J, Jadavji NM. (2022) The impact of homocysteine on ischemic stroke and dementia: an updated review of clinical studies and mechanisms in Advances in Health and Disease. Nova Science Publishers Inc.
Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T, Malysheva O, Caudill M, Jadavji NM. (2023) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring, Neural Regeneration Research. 18:2443-2448.
PREPRINT: Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T, Malysheva O, Caudill M, Jadavji NM (2022) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring. https://www.biorxiv.org/content/10.1101/2022.09.28.509960v1
17. Gyllian Yahn, MBS - Master of Biomedical Science and Doctor of Dental Medicine Student
Current position: Dental Student, Midwestern University
Publications:
Yahn GB, Abato JE, Jadavji NM (2021) Role of vitamin B12 deficiency in ischemic stroke risk and outcome. Neural Regen Res 16(3):470-474.
Yahn GB, Leoncio J, Jadavji NM (2021) The role of dietary supplementation of one-carbon metabolism on stroke outcome. Current Opinion in Clinical Nutrition and Metabolic Care: doi: 10.1097/MCO.0000000000000743 (invited)
Yahn GB, Wasek B, Bottiglieri T, Malysheva O, Caudill MA, Jadavji NM. (2021) A dietary vitamin B12 deficiency impairs motor function and changes neuronal survival and choline metabolism after ischemic stroke to the sensorimotor cortex in middle aged male and female mice. https://www.biorxiv.org/content/10.1101/2021.08.17.456684v3
Marella P, Yahn GB, Kang J, Jadavji NM. (2022) The impact of homocysteine on ischemic stroke and dementia: an updated review of clinical studies and mechanisms in Advances in Health and Disease. Nova Science Publishers Inc.
Yahn GB, Wasek B, Bottiglieri T, Malysheva O, Caudill MA, Jadavji NM (2023) A dietary vitamin B12 deficiency impairs motor function and changes neuronal survival and choline metabolism after ischemic stroke to the sensorimotor cortex in middle aged male and female mice. Nutritional Neuroscience, In Press https://doi.org/10.1080/1028415X.2023.2188639.
16. Sapna Viridi, MBS - Doctor of Osteopathic Medicine Student
Current position: Doctor of Osteopathic Medicine student, Midwestern University
Publications:
Virdi S, Jadavji NM* (2022) The impact of maternal folates on brain development and function after birth. Metabolites. 12(9): 876. (invited)
Virdi S, McKee AM, Nuthi M, Jadavji NM* (2023). The role of one-carbon metabolism on healthy brain aging. Nutrients. 15: 3891. (invited)
15. Jesse Jauhal, B.S. - Master of Biomedical Sciences Student
Current position: Dental Student, Midwestern University
Publication:
Clementson M, Jauhal J, Jadavji NM (2023) Dietary B-vitamins deficiencies and maternal over supplementation on neurodevelopment: an updated narrative. Vitamins and Minerals in Neurological Disorders. Editor: Colin Martin, Vinood Patel, and Victor Preedy. Elsevier. p661-672. (invited).
Clementson M, Jauhal J, Jadavji NM (2023) Dietary B-vitamins deficiencies and maternal over supplementation on neurodevelopment: an updated narrative. Vitamins and Minerals in Neurological Disorders. Editor: Colin Martin, Vinood Patel, and Victor Preedy. Elsevier. (invited).
PREPRINT Hurley L, Jauhal J, Ille S, Pull K, Malysheva OV, Jadavji NM. (2023) Maternal dietary deficiencies in one-carbon metabolism during early neurodevelopment result in larger damage volume, reduced neurodegeneration and neuroinflammation and changes in choline metabolites after ischemic stroke in middle-aged offspring. https://www.biorxiv.org/content/10.1101/2023.02.15.528759v1
14. Jeemin Kang, MA - Doctor of Osteopathic Medicine Student
Current position: Medical Student, Midwestern University
Publications:
Marella P, Yahn GB, Kang J, Jadavji NM. (2022) The impact of homocysteine on ischemic stroke and dementia: an updated review of clinical studies and mechanisms in Advances in Health and Disease. Nova Science Publishers Inc.
Pull K, Folk R, Kang J, Jackson S, Gusek B, Esfandiarei M, Jadavji NM. (2022) Maternal dietary choline deficiencies during pregnancy and lactation reduce cerebral blood flow in 3-month-old female mice offspring following ischemic stroke to the sensorimotor cortex. https://www.biorxiv.org/content/10.1101/2022.08.23.505040v1
Pull K, Folk R, Kang J, Jackson S, Gusek B, Esfandiarei M, Jadavji NM (2023) Maternal dietary choline deficiencies during pregnancy and lactation reduce cerebral blood flow in 3-month-old female mice offspring following ischemic stroke to the sensorimotor cortex. American Journal of Physiology – Heart and Circulatory Physiology: In press
13. Sarah Coonrod, BSc. - College Veterinary Medicine Fellow, Summer 2021
Current position: Veterinary Student
Publications
PREPRINT: Yaldiko A, Coonrod S, Marella P, Hurley L, Jadavji NM. Maternal dietary deficiencies in folic acid or choline reduce primary neuron viability after exposure to hypoxia through increased levels of apoptosis. https://www.biorxiv.org/content/10.1101/2023.12.09.570894v1
Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T, Malysheva O, Caudill M, Jadavji NM. (2023) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring, Neural Regeneration Research. 18:2443-2448.
PREPRINT: Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T, Malysheva O, Caudill M, Jadavji NM (2022) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring. https://www.biorxiv.org/content/10.1101/2022.09.28.509960v1
12. Agnes S. Pascual, M.S. – Senior Research Specialist
Publications:
Poole J, Jasbi J, Pascual AS, North S, Kwatra N, Weissig V, Gu H, Bottiglieri T, Jadavji NM. (2022) Ischemic stroke and dietary vitamin B12 deficiency in old-aged females impaired motor function, increased ischemic damage size, and changed metabolite profiles in brain and cecum tissue. Nutrients, 14(14), 2960; https://doi.org/10.3390/nu14142960
PREPRINT: Poole J, Jasbi J, Pascual AS, North S, Kwatra N, Weissig V, Gu H, Bottiglieri T, Jadavji NM. Ischemic stroke and dietary vitamin B12 deficiency in old-aged females impaired motor function, increased ischemic damage size, and changed metabolite profiles in brain and cecum tissue. https://www.biorxiv.org/content/10.1101/2022.04.04.487028v2
Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T, Malysheva O, Caudill M, Jadavji NM. (2023) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring, Neural Regeneration Research. 18:2443-2448.
PREPRINT: Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T, Malysheva O, Caudill M, Jadavji NM (2022) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring. https://www.biorxiv.org/content/10.1101/2022.09.28.509960
11. McCoy Clementson, B.S. - Doctor of Osteopathic Medicine Student
(Kenneth Saurez Research Fellow)
Current position: Emergency Medicine Resident
Publications:
Clementson M, Jauhal J, Jadavji NM (2023) Dietary B-vitamins deficiencies and maternal over supplementation on neurodevelopment: an updated narrative. Vitamins and Minerals in Neurological Disorders. Editor: Colin Martin, Vinood Patel, and Victor Preedy. Elsevier. (invited).
Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T, Malysheva O, Caudill M, Jadavji NM. (2023) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring, Neural Regeneration Research. 18:2443-2448.
PREPRINT: Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T, Malysheva O, Caudill M, Jadavji NM (2022) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring. https://www.biorxiv.org/content/10.1101/2022.09.28.509960v1
10. Joshua Poole, B.S. - Doctor of Osteopathic Medicine Student (Kenneth Saurez Research Fellow)
Current position: Anesthesia Resident at UT Houston
Publications:
Poole J, Jasbi J, Pascual AS, North S, Kwatra N, Weissig V, Gu H, Bottiglieri T, Jadavji NM. (2022) Ischemic stroke and dietary vitamin B12 deficiency in old-aged females impaired motor function, increased ischemic damage size, and changed metabolite profiles in brain and cecum tissue. Nutrients, 14(14), 2960; https://doi.org/10.3390/nu14142960
PREPRINT: Poole J, Jasbi J, Pascual AS, North S, Kwatra N, Weissig V, Gu H, Bottiglieri T, Jadavji NM. (2022) Ischemic stroke and dietary vitamin B12 deficiency in old-aged females impaired motor function, increased ischemic damage size, and changed metabolite profiles in brain and cecum tissue. https://www.biorxiv.org/content/10.1101/2022.04.04.487028v2
9. Shaley Jackson, B.Sc. - Research Assistant
Current position: Veterinary student, Midwestern University
Publications:
Pull K, Folk R, Kang J, Jackson S, Gusek B, Esfandiarei M, Jadavji NM. (2022) Maternal dietary choline deficiencies during pregnancy and lactation reduce cerebral blood flow in 3-month-old female mice offspring following ischemic stroke to the sensorimotor cortex. https://www.biorxiv.org/content/10.1101/2022.08.23.505040v1
Pull K, Folk R, Kang J, Jackson S, Gusek B, Esfandiarei M, Jadavji NM (2023) Maternal dietary choline deficiencies during pregnancy and lactation reduce cerebral blood flow in 3-month-old female mice offspring following ischemic stroke to the sensorimotor cortex. American Journal of Physiology – Heart and Circulatory Physiology: In press
8. Sean North, B.Sc. - Research Assistant
Current position: Medical student, Midwestern University
Publications
Poole J, Jasbi J, Pascual AS, North S, Kwatra N, Weissig V, Gu H, Bottiglieri T, Jadavji NM. (2022) Ischemic stroke and dietary vitamin B12 deficiency in old-aged females impaired motor function, increased ischemic damage size, and changed metabolite profiles in brain and cecum tissue. Nutrients, 14(14), 2960; https://doi.org/10.3390/nu14142960
PREPRINT: Poole J, Jasbi J, Pascual AS, North S, Kwatra N, Weissig V, Gu H, Bottiglieri T, Jadavji NM. Ischemic stroke and dietary vitamin B12 deficiency in old-aged females impaired motor function, increased ischemic damage size, and changed metabolite profiles in brain and cecum tissue. https://www.biorxiv.org/content/10.1101/2022.04.04.487028v2
7. Neha Kwatra, B.Sc. - Research Assistant
Current position: Dentist and Captain in the US Air Force
Publications:
Kwarta N, Jadavji NM. (2020) How changes in our genes impact outcome after stroke. Atlas of Science. https://atlasofscience.org/how-changes-in-our-genes-impact-outcome-after-stroke/
Burgess K, Bennett C, Mosnier H, Kwatra N, Bethel B, Jadavji NM (2020) The antioxidant role of one-carbon metabolism on stroke. Antioxidants. 9(11):1141 (invited)
Bennett C, Green J, Ciancio M, Goral J, Pitstick L, Pytynia M, Meyer A, Kwatra N, Jadavji NM*. (2021) Dietary folic acid deficiency impacts hippocampal morphology and cortical acetylcholine metabolism in adult male and female mice. Nutritional Neuroscience: In Press
Poole J, Jasbi J, Pascual AS, North S, Kwatra N, Weissig V, Gu H, Bottiglieri T, Jadavji NM. Ischemic stroke and dietary vitamin B12 deficiency in old-aged females impaired motor function, increased ischemic damage size, and changed metabolite profiles in brain and cecum tissue. https://www.biorxiv.org/content/10.1101/2022.04.04.487028v2
Poole J, Jasbi J, Pascual AS, North S, Kwarta N, Weissig V, Gu H, Bottiglieri T, Jadavji NM. (2022) Ischemic stroke and dietary vitamin B12 deficiency in old-aged females impaired motor function, increased ischemic damage size, and changed metabolite profiles in brain and cecum tissue. Nutrients, 14(14), 2960; https://doi.org/10.3390/nu14142960
6. Jeannine Leoncio, B.S. - Research Assistant
Current Position: Pharmacy Student, Midwestern University
Publication:
Yahn GB, Leoncio J, Jadavji NM The role of dietary supplementation of one-carbon metabolism on stroke outcome. Current Opinion in Clinical Nutrition and Metabolic Care: doi: 10.1097/MCO.0000000000000743 (invited)
5. Calli Bennett, B.Sc. - Doctor of Osteopathic Medicine Student (Kenneth Saurez Research Fellow)
Current position: OBGYN Resident
Publications
Burgess K, Bennett C, Mosnier H, Kwatra N, Bethel B, Jadavji NM (2020) The antioxidant role of one-carbon metabolism on stroke. Antioxidants. 9(11):1141 (invited)
Bennett C, Green J, Ciancio M, Goral J, Pitstick L, Pytynia M, Meyer A, Kwatra N, Jadavji NM*. (2021) Dietaryfolic acid deficiency impacts hippocampal morphology and cortical acetylcholine metabolism in adult male and female mice. Nutritional Neuroscience: In Press
Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T, Malysheva O, Caudill M, Jadavji NM. (2023) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring, Neural Regeneration Research. 18:2443-2448.
PREPRINT: Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T, Malysheva O, Caudill M, Jadavji NM (2022) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring. https://www.biorxiv.org/content/10.1101/2022.09.28.509960v1
4. Kassidy Burgess, BS - College of Veterinary Medicine Fellow
Current Position: Associate Veterinarian at Lakefield Veterinary Group
Publications
Burgess K, Bennett C, Mosnier H, Kwatra N, Bethel B, Jadavji NM. (2020) The antioxidant role of one- carbon metabolism on stroke. Antioxidants. 9(11):1141 (invited)
3. Forrest Bethel, MSc - Doctor of Osteopathic Medicine Student (Kenneth Saurez Research Fellow)
Current position: Surgery Resident
Publication
Burgess K, Bennett C, Mosnier H, Kwatra N, Bethel B, Jadavji NM. (2020) The antioxidant role of one-carbon metabolism on stroke. Antioxidants. 9(11):1141 (invited)
2. Chelsea Adamson, MPH – Research Assistant
Current position: Supervisor of Molecular Operations, Solid Tumor at Caris Life Sciences
Publication
Al Rubaye H, Adamson C, Jadavji NM (2020) The role of maternal diet on offspring gut microbiota development. Journal of Neuroscience Research. PMID: 32112450
1. Jamie Abato, BSc - Research Assistant
Current position: Veterinary Technician, Basking Ridge Animal Hospital
Publications
Abato JE, Moftah M, Cron GO, Smith PD, Jadavji NM*. (2020) Methylenetetrahydrofolate reductase deficiency alters cellular response after ischemic stroke in male mice. Nutritional Neuroscience. http://dx.doi.org/10.1080/1028415X.2020.1769412.
Yahn GB, Abato JE, Jadavji NM (2021) Role of vitamin B12 deficiency in ischemic stroke risk and outcome. Neural Regen Res 16(3):470-474.